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The main goal of our lab is to understand the function of the hippocampal and para-hippocampal circuits in the normal and the epileptic brain. We are interested on how complex patterns of activity are generated with a special emphasis in the cellular and synaptic rules that govern circuit dynamics. To tackle these questions we exploit modern techniques for selective interrogation of neuronal circuits with high-density arrays coupled to cell-type specific opto and chemogenetics. We combine electrophysiological and imaging tools with behavioral assessments to relate microcircuit function and dysfunction with cognition. We focus in different forms of activity, including several types of oscillations (ripples, fast ripples, theta and gamma) and epileptiform events.

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